Publications

19. Blazeski A , Floryan MA, Zhang Y, Fajardo-Ramírez OR,  Meibalan  E, Ortiz-Urbina  J, Angelidakis  E, Shelton SE, Kamm  RD, García-Cardeña G. Engineering microvascular networks using a KLF2  reporter to probe flow-dependent endothelial cell function. Biomaterials (2024). 

18. He J, Blazeski A , Nilanthi U, Menéndez J, Pirani SC, Levic DS, Bagnat M, Singh MK, Raya JG, García-Cardeña G, Torres-Vázquez J. Plxnd1-mediated mechanosensing of blood flow controls the caliber of the Dorsal Aorta via the transcription factor Klf2. bioRxiv (2024).

17. Linna-Kuosmanen S, Schmauch E, Galani K, Ojanen J, Boix CA, Örd T, Toropainen A, Singha PK, Moreau PR, Harju K,  Blazeski A , Segerstolpe Å, Lahtinen V, Hou L, Kang K, Meibalan E, Agudelo LZ, Kokki H, Halonen J, Jalkanen J, Gunn J, MacRae CA, Hollmén M, Hartikainen J, Kaikkonen MU, García-Cardeña G, Tavi P, Kiviniemi T, Kellis M. Transcriptomic and spatial dissection of human  ex vivo right atrial tissue reveals proinflammatory microvascular changes in ischemic heart disease.  Cell Reports Medicine 5(5), 101556 (2024).

16. Chen S, Blazeski A , Zhang S, Shelton SE, Offeddu GS, Kamm RD. Development of a perfusable, hierarchical microvasculature-on-a-chip model. Lab on a Chip  23, 4552-4564 (2023). doi:10.1039/D3LC00512G.

15. Grass M, McDougal AD, Blazeski A , Kamm RD, García-Cardeña G, Dewey CF. A computational model of cardiomyocyte metabolism predicts unique reperfusion protocols capable of reducing cell damage during ischemia/reperfusion. Journal of Biological Chemistry  298(5), 101693 (2022).

14. Duong T, Rose R, Blazeski A , Fine N, Woods CE, Thole JF, Sotoodehnia N, Soliman EZ, Tung L, McCallion AS, Arking DE. Development and optimization of an in vivo electrocardiogram recording method and analysis program for adult zebrafish.  Disease Models & Mechanisms 14(8), (2021).

13. Hawthorne RN, Blazeski A , Lowenthal J, Kannan S, Teuben R, DiSilvestre D, Morrissette-McAlmon J, Saffitz JE, Boheler KR, James CA, Chelko SP, Tomaselli G, Tung L. Altered Electrical, Biomolecular, and Immunologic Phenotypes in a Novel Patient-Derived Stem Cell Model of Desmoglein-2 Mutant ARVC. J Clin Med 10(14), (2021).

12. Blazeski A , Zhu R, Ewoldt J, Boheler KR, Tung L. Functional properties of engineered heart slices incorporating human induced pluripotent stem cell-derived cardiomyocytes. Stem Cell Reports  12(5), 982 (2019).

11. Blazeski A* , Lowenthal J*, Wang Y, Teuben R, Zhu R, Gerecht S, Tomaselli G, Tung L. Engineered Heart Slice Model of Arrhythmogenic Cardiomyopathy Using Plakophilin-2 Mutant Myocytes. Tissue Engineering Part A  25(9-10), 725 (2018). Journal Cover

10. Morrissette‐McAlmon J, Blazeski A , Somers S, Kostecki G, Tung L, Grayson WL. Adipose-derived perivascular mesenchymal stromal/stem cells promote functional vascular tissue engineering for cardiac regenerative purposes. Journal of Tissue Engineering and Regenerative Medicine  12(2), e962 (2017).

9.  Ong CS, Fukunishi T, Nashed A, Blazeski A , Zhang H, Hardy S, DiSilvestre D, Vricella L, Conte J, Tung L, Tomaselli G, Hibino N. Creation of Cardiac Tissue Exhibiting Mechanical Integration of Spheroids Using 3D Bioprinting. Journal of Visualized Experiments  e55438, (2017).

8.  Ong CS, Fukunishi T, Zhang H, Huang CY, Nashed A, Blazeski A , DiSilvestre D, Vricella L, Conte J, Tung L, Tomaselli GF, Hibino N. Biomaterial-Free Three-Dimensional Bioprinting of Cardiac Tissue using Human Induced Pluripotent Stem Cell Derived Cardiomyocytes. Scientific Reports  7, 4566 (2017).

7.  Blazeski A* , Kostecki GM*, Tung L. Engineered heart slices for electrophysiological and contractile studies. Biomaterials  55, 119-128 (2015).

6. Zhu R, Blazeski A , Poon E, Costa K, Tung L, Boheler KR. Physical developmental cues for the maturation of human pluripotent stem cell-derived cardiomyocytes. Stem Cell Research & Therapy  5, 117 (2014).

5.  Thompson SA, Blazeski A , Copeland CR, Cohen DM, Chen CS, Reich DM, Tung L. Acute slowing of cardiac conduction in response to myofibroblast coupling to cardiomyocytes through N-cadherin. Journal of Molecular and Cellular Cardiology  68, 29-37 (2014).

4.  Blazeski A , Zhu R, Hunter DW, Weinberg SH, Boheler KR, Tung L. Electrophysiological and contractile function of cardiomyocytes derived from human embryonic stem cells. Progress in Biophysics & Molecular Biology  110, 178-95 (2012).

3.  Blazeski A , Zhu R, Hunter DW, Weinberg SH, Zambidis ET, Tung L. Cardiomyocytes derived from human induced pluripotent stem cells as models for normal and diseased cardiac electrophysiology and contractility. Progress in Biophysics & Molecular Biology  110, 166-77 (2012).

2.  Blazeski A , Kozloff K, Scott PJH. Besilesomab for imaging inflammation and infection in peripheral bone in adults with suspected osteomyelitis.  Reports in Medical Imaging 3, 17-27 (2010).

1. Zhao K, Berglund L, Blazeski A , Tung W-L., and An K-N. A Method for Quantifying Pipette Ergonomics. The Annual Meeting for the American Society of Biomechanics , State College, PA (2009).

* indicates co-first author

PATENTS

Blazeski A, Tung L, “Grid of responses indicating drug sensitivity” U.S. Patent Application 62/826,030, filed March 29, 2019.

Tung L, Blazeski A, “Engineered cardiac derived compositions and methods of use” U.S. Patent 20170173215, issued January 22, 2019.